Course Descriptions - Undergraduate Calendar 2013-2014

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C H E M I S T R Y 

Note

  1. Because of space and equipment limitations in laboratory courses, priority must be given to students whose Academic Plans require those courses.

CHEM 00s


CHEM 1 LEC 0.00Course ID: 010181
Pre-University Chemistry
Essential preparation for first year chemistry courses. Formulae, nomenclature, stoichiometry, an introduction to thermochemistry, solution chemistry, chemical equilibria, acids, bases, oxidation-reduction reactions, kinetics and bonding.
[Note: Successful completion of this courses fulfills the University admission requirements where high school chemistry is necessary. No University credit.]
Only offered Online

CHEM 100s


CHEM 120 LEC,TST,TUT 0.50Course ID: 004036
Physical and Chemical Properties of Matter
The stoichiometry of compounds and chemical reactions. Properties of gases. Periodicity and chemical bonding. Energy changes in chemical systems. Electronic structure of atoms and molecules; correlation with the chemical reactivity of common elements, inorganic and organic compounds.
[Note: Offered: F, W. Science students must also take CHEM 120L. Successful completion of Grade 12 U Calculus and Vectors and Grade 12 U Chemistry or equivalent courses is required]
Also offered Online

CHEM 120L LAB 0.25Course ID: 004037
Chemical Reaction Laboratory 1
Selected experiments for students taking CHEM 120.
[Note: Students who are not taking, or who have not previously taken CHEM 120, will be removed from CHEM 120L. Offered: F]

CHEM 123 LEC,TST,TUT 0.50Course ID: 004040
Chemical Reactions, Equilibria and Kinetics
Properties of liquids and solutions. Introduction to chemical equilibria. Principles of acid-base equilibria, solubility and electrochemical processes. Chemical kinetics.
[Note: Science students must also take CHEM 123L. Offered: W,S]
Prereq: CHEM 120
Also offered Online

CHEM 123L LAB,TUT 0.25Course ID: 004041
Chemical Reaction Laboratory 2
Selected experiments for students taking CHEM 123.
[Note: Students who are not taking, or who have not previously taken CHEM 123, will be removed from CHEM 123L. Offered: W,S]

CHEM 140 LAB,LEC 0.50Course ID: 012688
Introduction to Scientific Calculations
The use of software packages, such as Excel and Mathcad, for basic calculations, data analysis, regression analysis, plotting of scientific graphs, data manipulation, and equation solving will be covered, with an emphasis placed upon chemical and biochemical concepts and applications. [Offered: F,W,S]
Prereq: CHEM 120; Not open to Mathematics students

CHEM 200s


CHEM 209 LEC,TUT 0.50Course ID: 012080
Introductory Spectroscopy and Structure
The nature of electromagnetic radiation and an elementary outline of quantum mechanics in one dimension. For each of microwave, infrared, Raman, electronic, photoelectron, and nuclear magnetic resonance spectroscopy, the nature of the molecular energy levels involved and the type of molecular information that can be obtained using it are examined. Introduction to diffraction methods. [Offered: F]
Prereq: CHEM 120 or NE 121.
Antireq: CHEM 129

CHEM 212 LEC,TUT 0.50Course ID: 004048
Structure and Bonding
An introduction to the principles of chemical structure and bonding, with emphasis on their application to inorganic systems. Topics include: atoms, orbitals, and periodicity; localized bonding models; symmetry and group theory; and molecular orbital theory. The subjects treated in this course are foundational components for advanced studies in all areas of chemistry. [Offered: W,S]
Prereq: CHEM 120, 123; Honours students only

CHEM 217 LEC 0.50Course ID: 013241
Chemical Bonding
Atomic and molecular structure. Molecular symmetry. Localized bonding models. Molecular orbital theory. Structures of solids. [Not open to students in the following plans: Biochemistry, Chemical Physics, Chemistry, Computational Science (Biochemistry Specialization), Computational Science (Chemistry Specialization), Geochemistry, Science and Business (Biochemistry Specialization), Science and Business (Chemistry Specialization). Offered: F]
Prereq: (CHEM 120 and 123) or NE 121.
Antireq: CHEM 212
Only offered Online

CHEM 220 LEC,TUT 0.50Course ID: 004052
Intro Analytical Chemistry
Quantitative and analytical chemistry including ionic equilibria, classical and more recent methods. Emphasis on planning and decision-making in the analytical process. [Offered: F]
Prereq: CHEM 123; Honours Science Programs.
Antireq: CHEM 228

CHEM 220L LAB 0.25Course ID: 004053
Analytical Chemistry Lab 1
Selected experiments for students taking CHEM 220 or 228. [Offered: F, W]
Prereq: CHEM 123L; Honours Science Programs.
Coreq: CHEM 220 or 228.
Antireq: CHEM 228L

CHEM 221 LEC,TUT 0.50Course ID: 004054
Multi-Component Analysis
Instrumental analytical chemistry, including traditional and more recent methods. Emphasis on planning and decision-making in the analytical process. [Offered W,S]
Prereq: CHEM 220, 220L.

CHEM 224L LAB,TUT 0.50Course ID: 004058
Analytical Chemistry Laboratory 2
Extensive lab experience for students who have taken CHEM 220. [Offered: W,S]
Prereq: CHEM 220 and CHEM 220L; Honours Science programs

CHEM 228 LEC 0.50Course ID: 004059
Chemical Analysis
An introduction to methods of quantitative chemical analysis. [Not open to students in the following plans: Biochemistry, Chemical Physics, Chemistry, Geochemistry, Science and Business (Biochemistry Specialization), Science and Business (Chemistry Specialization), Offered: W]
Prereq: CHEM 123.
Antireq: CHEM 220

CHEM 233 LEC,TUT 0.50Course ID: 004060
Fundamentals of Biochemistry
Chemistry of amino acids, carbohydrates, lipids and nucleic acids, with special emphasis on representative proteins and enzymes, including hemoglobin, cytochrome c and chymotrypsin. [Offered: W,S]
Prereq: CHEM 264 or 28/262; Honours Biochemistry, Biology, Chemistry or Environmental Science.
Antireq: CHEM 237, NE 224

CHEM 237 LEC,TST,TUT 0.50Course ID: 004061
Introductory Biochemistry
An introduction to the chemistry of amino acids, carbohydrates, lipids and nucleic acids. Structure and properties of proteins and enzymes. [Offered: F,W, S]
Prereq: CHEM 28/262 or 264 or 266.
Antireq: CHEM 233, NE 224
Also offered Online

CHEM 237L LAB,TUT 0.25Course ID: 004062
Introductory Biochemistry Laboratory
Selected experiments for students taking CHEM 237. [Offered: F,W, S]
Coreq: CHEM 237

CHEM 240 LEC,TUT 0.50Course ID: 012081
Mathematical Methods for Chemistry
Mathematical techniques useful for chemistry students. Introduction to complex numbers, plus topics chosen from: calculus; differential equations; vector spaces and vector algebra; matrices and determinants; elementary probability theory; basic group theory and symmetry. Applications to problems of chemical interest. [Offered: F]
Prereq: One of MATH 128, 138 or 148; Not open to students in the Faculty of Mathematics

CHEM 250L LAB,SEM 0.25Course ID: 004063
Physical Chemistry Laboratory 1
Selected experiments for students in year two. [Offered: F]
Prereq: CHEM 140 (formerly CHEM 140L); Honours students only

CHEM 254 LEC,TUT 0.50Course ID: 004064
Introductory Chemical Thermodynamics
An introduction to the first, second and third laws of thermodynamics and the application of these laws to ideal systems, mixtures, and chemical reactions. Thermodynamic principles are used to study changes in state, including phase changes, and to establish the link between the equilibrium constant and the properties of the substances involved in a chemical reaction. [Offered: W,S]
Prereq: CHEM 123; One of MATH 128, 138, 148; Honours students only.
Antireq: PHYS 258/358/ECE 403

CHEM 262 LEC,TUT 0.50Course ID: 004029
Organic Chemistry for Engineering and Bioinformatics Students
Bonding, structure and nomenclature in organic chemistry. Physical properties and simple reactions associated with the important functional groups. [Offered: F,W; previously numbered CHEM 28]
Prereq: Chemical Engineering or Bioinfomatics students.
Coreq: CHEM 262L (for Engineering students).
Antireq: CHEM 264, 266, NE 122

CHEM 262L LAB 0.25Course ID: 004030
Organic Chemistry Laboratory for Engineering Students
Selected experiments for engineering students taking CHEM 262. [Offered: F,W; previously numbered CHEM 28L]
Coreq: CHEM 262 (for Engineering students)

CHEM 264 LEC,TUT 0.50Course ID: 004068
Organic Chemistry 1
Structure and bonding in organic chemistry. Isomerism and stereoisomerism in organic compounds. Acidity of organic compounds and substituent effects on acidity. Reaction mechanisms and energetics. Chemistry of alkanes, haloalkanes, alcohols and ethers, alkenes and alkynes. [Offered: F]
Prereq: CHEM 123 or 125; Honours Programs only.
Antireq: CHEM 28/262, 266, NE 122

CHEM 265 LEC,TUT 0.50Course ID: 004069
Organic Chemistry 2
Nucleophilic addition and substitution at CO carbon. Aromaticity and simple MO theory of conjugated systems. Electrophilic and nucleophilic aromatic substitution reactions. Applications of spectroscopic techniques in organic chemistry. [Offered: W,S]
Prereq: CHEM 264; Honours Science students only.
Antireq: CHEM 38, 267

CHEM 265L LAB 0.25Course ID: 004070
Organic Chemistry Laboratory 1
Selected experiments for students taking CHEM 265. [Offered: W,S]
Prereq: Honours Science students only.
Coreq: CHEM 265

CHEM 266 LEC,TST 0.50Course ID: 004071
Basic Organic Chemistry 1
Discussions of the structure, nomenclature and reactions of important classes of organic compounds. Stereochemistry and its role in reaction mechanisms. A detailed look at carboxylic acids and their derivatives. [Offered: F]
Prereq: CHEM 120, 123.
Antireq: CHEM 28/262, 264, NE 122
Also offered Online

CHEM 266L LAB 0.25Course ID: 004072
Organic Chemistry Laboratory
Selected experiments for students taking (or who have taken) CHEM 266.
[Note: Lab alternate weeks. Offered: F]
Prereq: CHEM 123L.
Coreq: CHEM 266

CHEM 267 LEC,TST 0.50Course ID: 004073
Basic Organic Chemistry 2
A continuation of the concepts of CHEM 266, including material on amines, aromatics, carbohydrates and lipids. Introduction to nuclear magnetic resonance and infrared spectroscopy. [Offered: W]
Prereq: CHEM 28/262 or 264 or 266.
Antireq: CHEM 38, 265, NE 122
Also offered Online

CHEM 267L LAB 0.25Course ID: 004074
Organic Chemistry Laboratory
Selected experiments for students taking CHEM 267.
[Note: Lab alternate weeks. Offered: W]
Prereq: CHEM 266L.
Coreq: CHEM 267

CHEM 300s


CHEM 305 LEC,TUT 0.50Course ID: 004077
Atmospheric Chemistry and Physics
The chemistry and physics of the terrestrial atmosphere, with emphasis on the operation of major anthropogenic influences, such as ozone depletion, the greenhouse effect and tropospheric systems, such as photochemical smog. Other planetary atmospheres will be discussed in the context of their implications for the evolution of the earth's atmosphere. [Offered: W]
Prereq: CHEM 254, 350
(Cross-listed with EARTH 305)

CHEM 305L LAB 0.25Course ID: 010355
Atmospheric Modelling Laboratory
This course provides an introduction to modern regional air quality modelling. The models used are Models-3, the U.S. Environmental Protection Agency's tropospheric modelling framework and MM-5, the meteorology model developed by the U.S. National Center for Atmospheric Research. The course covers the major elements in regional air quality modelling: emissions databases, chemical modelling, and the role of meteorology. A team-oriented modelling project relevant to Southern Ontario air quality will be carried out. [Offered: W]
Coreq: CHEM 305
(Cross-listed with EARTH 305L)

CHEM 310 LEC,TUT 0.50Course ID: 004078
Transition Element Compounds and Inorganic Materials
The inorganic, organic and solid state chemistry of the d-block elements. The structure and physical properties of coordination compounds and transition metal containing solids. The role of transition metal organometallics in catalysis. [Offered: F]
Prereq: CHEM 212; Honours Science students only

CHEM 310L LAB,SEM 0.50Course ID: 004079
Inorganic Chemistry Laboratory 2
Synthesis of transition and non-transition metal compounds. Characterization of compounds using IR, UV-VIS and NMR spectroscopy. [Offered: F]
Prereq: Honours Science students only.
Coreq: CHEM 310

CHEM 313 LEC 0.50Course ID: 004083
Main Group and Solid State Chemistry
This course provides a detailed examination of the structure and bonding in main group and solid state compounds, including valence bond and molecular orbital theory for describing electronic structures, Hueckel and extended Hueckel approximations. Structures of simple solids, including close packing of spheres and derived ionic lattice types; aspects of chemical crystallography, Bravais lattices, point groups, space groups, crystal planes, and X-ray diffraction; Ionic interactions in gases and solution; the thermodynamics of acid-base interactions; descriptive chemistry and characterization of main group element compounds. [Offered: W]
Prereq: CHEM 212.
Antireq: CHEM 213

CHEM 313L LAB,SEM 0.25Course ID: 011572
Inorganic Chemistry Laboratory 1
Introduction to synthetic inorganic chemistry. [Offered: W]
Prereq: Honours Students only.
Coreq: CHEM 313

CHEM 323 LEC 0.50Course ID: 004089
Analytical Instrumentation
Detailed study of selected instruments and instrumental methods. Introduction to chemometrics and to computer interfacing. [Offered: F]
Prereq: CHEM 221; CHEM 224L; Level at least 3A Honours Science programs

CHEM 331 LEC,TUT 0.50Course ID: 012194
Fundamentals of Metabolism 1
Thermodynamics of metabolism. Metabolism of carbohydrates and lipids. Chemistry of oxidative phosphorylation and photosynthesis. Emphasis is put on the role and chemical mechanisms of the enzymes in these processes [Offered: F]
Prereq: CHEM 233, 265.
Antireq: CHEM 333

CHEM 333 LEC 0.50Course ID: 004091
Metabolism 1
Metabolism of carbohydrates, lipids and amino acids. [Offered: F, W]
Prereq: CHEM 233 or 237 or NE 224 and CHEM 265 or 267.
Antireq: CHEM 331

CHEM 335L LAB,TUT 0.50Course ID: 004092
Advanced Biochemistry Laboratory
Selected experiments for students having completed or concurrently taking CHEM 331. Topics to be covered include: NMR, allostery, enzymology, electrophoresis, carbohydrates, lipids, photosynthesis, and respiration. [Offered: F,W]
Prereq: CHEM 233 or 237.
Coreq: (CHEM 331 or 333) and 357

CHEM 340 LAB,LEC,TUT 0.50Course ID: 012563
Introductory Computational Chemistry
Introduction to the theory and practice of computational methods used in chemistry. Use of molecular modeling software to investigate the electronic structure and geometry of molecules, to calculate potential energy surfaces for chemical reactions, and to predict and understand the behaviour of chemical systems. [Offered: W]
Prereq: CHEM 140 (formerly CHEM 140L); CHEM 129 or 209; CHEM 212 or 264

CHEM 350 LEC,TUT 0.50Course ID: 004093
Chemical Kinetics
Basic Chemical kinetics; treatment of kinetic data; complex reaction mechanisms; fast reactions; the canonical ensemble and the canonical partition function; statistical mechanics applied to chemistry; statistical theory of reaction rates. [Offered: W]
Prereq: CHEM 209, 240, 254; Honours Students only.

CHEM 350L LAB 0.50Course ID: 004094
Physical Chemistry Laboratory 2
Selected experiments for students in year three. [Offered: F]
Prereq: CHEM 250L; Honours Science

CHEM 356 LEC,TUT 0.50Course ID: 004067
Introductory Quantum Mechanics
Historical background; the differential equation approach to quantum mechanics; treatments of solvable problems such as the particle-in-a-box, harmonic oscillator, rigid rotator and the hydrogen atom; introduction to approximation methods for more complicated systems.
[Note: Formerly CHEM 256. Offered: F]
Prereq: CHEM 209, 240.
Antireq: PHYS 234

CHEM 357 LEC,TUT 0.50Course ID: 004101
Physical Biochemistry
The use of diffusion, ultracentrifugation, osmotic pressure, eletrophoresis and X-ray diffraction to study the properties of biopolymers. Hyperbolic and allosteric enzyme kinetics, inhibition and regulation. Some spectroscopies important to the life sciences. [Offered: W]
Prereq: CHEM 123, MATH 128; One of CHEM 233, 237, NE 224

CHEM 360 LEC,TUT 0.50Course ID: 004107
Organic Chemistry 3
Enolate alkylation and condensation reactions; conjugate addition reactions. Chemistry of amines and other nitrogen compounds. Pericyclic reactions and FMO theory. [Offered: W]
Prereq: CHEM 265; Honours Programs only

CHEM 360L LAB 0.50Course ID: 004108
Senior Organic Chemistry Laboratory
Selected microscale synthetic experiments for students in Year Three Chemistry and Biochemistry programs, including spectroscopic identification of organic compounds. [Offered: W]
Prereq: CHEM 265, 265L; Honours Programs only.
Coreq: CHEM 360

CHEM 370 LEC,TUT 0.50Course ID: 004190
Introduction to Polymer Science
Basic definitions and polymer nomenclature, molecular weight averages and distributions, constitutional and configurational isomerism, rubber elasticity, step-growth and free radical chain growth polymerizations, emulsion polymerization. [Offered: F]
Prereq: CHEM 254, (CHEM 265 or 267).
Antireq: CHE 542, NE 333

CHEM 381 LEC 0.50Course ID: 012199
Medicinal and Bioorganic Chemistry
Mechanisms of selected enzymes, vitamins/cofactors. Introduction to the structures and mechanism of action of selected classes of medicinal agents. [Offered: W]
Prereq: CHEM 233, 265

CHEM 382L LAB,TUT 0.50Course ID: 012200
Advanced Organic Synthesis Laboratory
A laboratory course intended for students in the Medicinal Chemistry Specialization of the Honours Chemistry plan. The purpose of this course is to introduce students to advanced laboratory techniques used in synthetic organic chemistry. [Offered: F]
Prereq: CHEM 360, 360L

CHEM 392A LAB 0.75Course ID: 004116
Research Project 1
Only for exchange students.

CHEM 392B LAB 0.75Course ID: 004117
Research Project 2
Only for exchange students.

CHEM 400s


CHEM 404 LEC,TUT 0.50Course ID: 004119
Physicochemical Aspects of Natural Waters
Organic (natural and synthetic) chemicals in the environment. Environmental fate of organic pollutants. Environmental (solar) photochemistry. Technologies for water and wastewater treatment (microorganisms in water purification, direct photolysis, advanced redox processes, municipal and industrial water treatment, groundwater treatment). [Offered: F]
Prereq: Level at least 3A

CHEM 410 LEC 0.50Course ID: 004126
Special Topics in Inorganic Chemistry
For a current list of offerings see the Undergraduate Officer.
[Note: Formerly CHEM 413. Offered: F, W]
Prereq: Level at least 3A

CHEM 420 LEC 0.50Course ID: 004139
Special Topics in Analytical Chem
For a current list of offerings see the Undergraduate Officer. [Formerly CHEM 425. Offered: F,W.]
Prereq: Level at least 3A

CHEM 430 LEC 0.50Course ID: 004152
Special Topics in Biochemistry
For a current list of offerings see the Undergraduate Officer.
[Note: Instructor may elect to use the third lecture hour for a tutorial or not at all. [Offered: F,W. Formerly CHEM 434]
Prereq: Level at least 3A; CHEM 331 or CHEM 333

CHEM 432 LEC,TUT 0.50Course ID: 004150
Metabolism 2
Properties and metabolism of porphyrins, purines, pyrimidines and biogenic amines. Biosynthesis and mode of action of selected cofactors. Structure-function relationships of enzymes. Regulation of enzyme activity. [Offered: F]
Prereq: CHEM 331 or 333

CHEM 433 LEC,TUT 0.50Course ID: 004151
Advanced Biochemistry
Nitrogen fixation. Assimilation of nitrogen. Amino acid metabolism. Metabolic regulation. Proteolytic enzymes, ubiquitin. Blood coagulation. Signal transduction and amplification. Biochemistry of nitric oxide. Biochemistry of vision. [Offered: W]
Prereq: CHEM 331 or 333

CHEM 440 LEC 0.50Course ID: 013002
Special Topics in Computational/Theoretical Chemistry
For a current list of offerings see the Undergraduate Advisor. [Offered: F,W]
Prereq: Level at least 3A Honours Science

CHEM 450 LEC 0.50Course ID: 004164
Special Topics in Physical Chemistry
For a current list of offerings see the Undergraduate Officer. [Formerly CHEM 452. Offered: F,W ]
Prereq: Level at least 3A

CHEM 460 LEC 0.50Course ID: 004183
Special Topics in Organic Chemistry
For a current list of offerings see the Undergraduate Officer.
[Note: Fomerly CHEM 465. Offered: F, W]
Prereq: CHEM 360; Level at least 3A

CHEM 464 LEC 0.50Course ID: 004182
Spectroscopy in Organic Chemistry
Elucidation and identification of organic structures by contemporary spectroscopic techniques. [Offered: F]
Prereq: CHEM 265

CHEM 470 LEC 0.50Course ID: 013003
Special Topics in Polymer Chemistry
For a current list of offerings see the Undergraduate Advisor. [Offered: F,W]
Prereq: CHEM 370

CHEM 481 LEC,TUT 0.50Course ID: 013360
Rational Design of Potential Drug Candidates
This course provides an introduction to strategies for design of potential drug candidates. It builds upon molecular modelling principles introduced in CHEM 340 and will apply them to specific problems in drug design. Topics include: conformational analysis, molecular mechanics, and molecular dynamics; computational studies of drug-receptor interactions, docking of small organic molecules to biological receptors, and alteration of molecular structures for improvement of bioactivity.
Prereq: (CHEM 233 or 237), 340/340L, 360

CHEM 482 LEC,TUT 0.50Course ID: 013361
Advanced Topics in Medicinal Chemistry
This course explores modern methods in drug discovery through the use of case studies and the participation of industrial medicinal chemists as guest speakers. Although topics and cases will vary from year to year, they will explore the following critical areas: specific enzyme inhibitors as drug candidates, design and synthesis of combinatorial libraries, high throughput screening methods and natural products including manipulation of secondary metabolism for production of analogues of natural product drug leads.
Prereq: (CHEM 233 or 237), 360

CHEM 494A PRJ 0.50Course ID: 004194
Research Project
Laboratory work on a senior year research project. Enrolment into this course requires permission of the CHEM 494 co-ordinator. See the CHEM 494 coordinator for course details. No credit or grade will be provided for this course until the two-term sequence CHEM 494A/B has been completed. CHEM 494A/B may not be taken concurrently without prior permission of the CHEM 494 co-ordinator.
Prereq: Level at least 4A Honours Chemistry, Biochemistry, Chemical Physics, Environmental Chemistry, Geochemistry

CHEM 494B PRJ 0.50Course ID: 009910
Research Project
A continuation of CHEM 494A. No credit or grade will be provided for this course until the two-term sequence CHEM 494A/B has been completed. CHEM 494A/B may not be taken concurrently without prior permission of the CHEM 494 co-ordinator.
Prereq: CHEM 494A

CHEM 495 PRJ 2.50Course ID: 010356
Advanced Research Project
This course is only for exchange students wishing to carry out an advanced research project during the fall term.
Department Consent Required
Prereq: Exchange students only

CHEM 496 PRJ 2.50Course ID: 010357
Advanced Research Project
This course is only for exchange students wishing to carry out a research project during the winter term.
Department Consent Required
Prereq: Exchange students only

CHEM 497 PRJ 2.50Course ID: 010358
Advanced Research Project
This course is only for exchange students wishing to carry out a research project during the spring term.
Department Consent Required
Prereq: Exchange students only